--- description: Whether you are a fresher or an experienced candidate, preparing for a chemistry interview can feel overwhelming. This guide on Chemistry interview questions title: Top 22 Chemistry Interview Questions and Answers (2026) image: https://career.guru99.com/wp-content/uploads/2014/08/chemistry-interview-questions.png --- [Skip to content](#main) Whether you are a fresher or an experienced candidate, preparing for a chemistry interview can feel overwhelming. This guide on Chemistry interview questions and answers is here to simplify the process. Covering basic concepts from BSc to more advanced topics suitable for MSc candidates, we aim to help you succeed in your interviews. Explore these Chemistry interview questions and enhance your confidence with clear, concise answers tailored to your level of expertise. [Free PDF Download: Chemistry Interview Questions](#cb9299a365) --- ## Basic Chemistry Questions for Interview ![Chemistry Interview Questions and Answers](https://career.guru99.com/wp-content/uploads/2024/10/chemistry-interview-questions-and-answers.png) ### 1) Explain the term Aliquot and Diluent? * **Aliquot:** It is a measured sub-volume of the original sample * **Diluent:** Material with which sample is diluted --- ### 2) What is molality? Molality is the number of solutes that are present in 1 kg of a solvent. --- ### 3) What is titration? Titration is a process to determine the molarity of a base or an acid. In this process, a reaction is carried out between the known volumes of a solution with a known concentration, against the known volume of a solution with an unknown concentration. --- **Don't Miss:** * [Technical Interview Questions and Answers (2026)](https://career.guru99.com/technical-interview-questions/ "Technical Interview Questions and Answers (2026)") * [Top 55 Medical School Interview Questions (2026)](https://career.guru99.com/medical-school-interview-questions-answers/ "Top 55 Medical School Interview Questions (2026)") * [Top 34 Nutritionist Interview Questions (2026)](https://career.guru99.com/nutritionist-interview-questions/ "Top 34 Nutritionist Interview Questions (2026)") * [51 Mechanical Engineering Interview Questions & Answers](https://career.guru99.com/mechanical-engineering-interview-questions/ "51 Mechanical Engineering Interview Questions & Answers") ### 4) What is a buffer? A buffer is an aqueous solution which has highly stable pH. It is a blend of a weak acid and its conjugate base or vice versa. On adding a small amount of base or acid to buffer, its pH hardly changes. --- ### 5) How does buffer work? In buffer when hydrogen ion is added, it will be neutralized by the base in the buffer. Hydroxide ion will be neutralized by the acid. On the overall pH of the buffer solution, these neutralization reactions will not show much effect. While when you select an acid as a buffer solution, try to use an acid that has a pH closed to your desired pH. This will help your buffer to achieve a nearly equivalent amount of acid and conjugate base, so that it will enable to neutralize as much as H+ and OH -. --- ### 6) What is a mole? Mole is the unit used to define the number of chemical substance present in a substance. It is the amount of substance which consists of the same number of chemical units as there are atoms in exactly 12 gram of pure carbon-12\. [](https://career.guru99.com/wp-content/uploads/2014/08/chemistry-interview-questions.png) Chemistry Interview Questions --- ### 7) How will you calculate how many moles of glucose present in 320 mL of 5.0 M of glucose solution? First step: Convert the volume from millilitres to litres * 320 X (1 litre/1000mL) = 0.320 L solution Second use the formula = M x V = 5.0 moles glucose/ litre solution X 0.320 L solution = 1.6 moles of glucose present in 320mL of solution --- ### 8) Explain what is the difference between fractionation and distillation? Both methods are used to separate the components present in the solution based on the boiling points. * **Distillation:** This technique is used when the boiling point of chemicals are different in the mixtures * **Fractionation:** This technique is used when the boiling point of chemicals are close to each other in the mixtures --- ### 9) Mention the formula to calculate pH of a solution? In order to calculate the pH of a solution you have to use the formula pH= -log \[H+\] or pH = -log \[H3O+\] --- ### 10) What is the difference between Molarity and Normality? Both techniques are used to the amount of chemical present in the solution. However, they are almost similar but differs in | **Molarity** | **Normality** | | ---------------------------------------------------------------------------- | ----------------------------------------------------------------------------------- | | Molarity is used to know the total amount of molecules in a 1-liter solution | Normality is used to know the total number of reactive units in 1 liter of solution | | It is expressed as moles of a compound per litre of solution | It is expressed in equivalent per litre | --- ## Advanced Chemistry Questions for Interview ### 11) What is Valency? Valency is a property of groups or atoms, equal to the number of atoms of hydrogen that the group or atom could combine with or displace it in forming compounds. [](https://career.guru99.com/wp-content/uploads/2014/08/chemistry.png) Chemistry Interview Questions --- ### 12) Define Avogadro’s law? According to Avogadro’s law, at the same temperature and pressure, an equal volume of gases contains the same number of molecules regardless of the chemical nature and physical properties. Avogadro’s number = 6.023 X 1023 --- ### 13) Explain what makes a molecule into organic molecule? In a molecule when a hydrogen atom is less than the ratio of the carbon atom, then such molecules are referred to as an organic molecule. [](https://career.guru99.com/wp-content/uploads/2014/08/atom-vector-SBI-300152302.jpg) atom --- ### 14) Which metal is used to extract copper from the solution of copper sulfate? Fe or ferrous is the metal that is used to extract copper from the solution of copper sulphate. --- ### 15) Explain what is the chemical composition of fat in the human body? The fat found in the human body is mainly composed of * Glycerides * Glycerides+Phospholipids * Glycolipids * Phosphoinositides * Tocopherol --- ### 16) What is the monomer of polyethylene? The monomer of polyethylene is ethylene (C₂H₄), which is a simple hydrocarbon molecule consisting of two carbon atoms double-bonded to each other and each bonded to two hydrogen atoms. During the polymerization process, ethylene molecules link together to form long chains, resulting in polyethylene, a common plastic material. --- ### 17) What is the formula you will use to calculate how many milliliters of 5.5 M NaOH are required to prepare 400 mL of 1.5M NaOH? To know the amount or volume of NaOH to prepare 400 mL of 1.5 M NaOH, we use formula M1 X V1 = M2 X V2 V1 = M2 X V2/ M1 But before that we will convert 400 mL into litre = 0.4 L 5.5 X V1 = 1.5 M x 0.4 L V1 = 1.5 M X 0.4L/ 5.5 V1= 0.10 L V1 = 100mL So, you need 100mL of 5.5 NaOH --- ### 18) Why graphite rod is used in nuclear reactor? A graphite rod is used in a nuclear reactor allows un-enriched uranium to be used as a nuclear fuel. --- ### 19) Mention how many milliliters is equal to 1 liter and how many microliters is equal to liter? * 1 millilitre = 0.001 litre * 1 microliter = 0.000001 litre --- ### 20) What is oxidation and reduction reaction? * **Oxidation =** When there is a loss of hydrogen or electrons OR gain of oxygen is known as Oxidation reaction. * **Reduction =** When there is a gain of hydrogen or electron OR loss of oxygen is known as a reduction reaction Example of oxidation-reduction reaction is observed in the human body when an electron is transferred into the cell and oxidation of glucose take place from which we get the energy. --- ### 21) What does iron ore consist of? Iron ore primarily consists of iron oxides, such as hematite (Fe₂O₃) and magnetite (Fe₃O₄). These compounds contain iron, which is extracted through smelting and refining processes to produce iron for various applications, including steel production. Additionally, iron ore may contain impurities like silica, alumina, phosphorus, and sulfur, which are typically removed during processing. --- ### 22) Explain what is dextro-rotatory and levorotatory? Levorotation and Dextrorotation are referred to the properties of plane polarized light when light rotates clockwise when it approaches the observer is then known as dextro-rotation, and when the light rotates anti-clockwise then it is referred as levorotation. A compound which exhibits a dextro-rotation is referred to as dextro-rotatory and which exhibits levorotation is referred to as levorotatory. ## Conclusion To excel in your Chemistry interview, it’s vital to practice basic and advanced questions. Doing so will boost your confidence, ensuring you’re fully prepared. Don’t forget to leave any challenging questions you’ve encountered in the comments section to help others. These interview questions will also help in your viva(orals) Share **You Might Like:** * [Technical Interview Questions and Answers (2026)](https://career.guru99.com/technical-interview-questions/) * [How to Write a Resume & CV with Format & Template Examples](https://career.guru99.com/sample-functional-resume/) * [Top 20 Common Interview Questions and Answers](https://career.guru99.com/common-job-interview-questions/) * [50 Most Common Interview Questions and Answers in HR round](https://career.guru99.com/how-to-answer-50-most-common-interview-questions/) ## 105 Comments 1. Number 19 isn’t correct. 1ml = 0.001L and so on [Reply](#comment-39930) 1. 1milliliter =0.0001 [Reply](#comment-43086) 1. 1 millilitre is one 1000th of a litre – therefore 1ml = 0.001L [Reply](#comment-49774) 1. updated! Thanks for pointing this out [Reply](#comment-55730) 1. How to prepare solution in ppm 2. Litre [Reply](#comment-233016) 1. milligrams per litre [Reply](#comment-276989) 3. 0.001 [Reply](#comment-284593) 2. Avogadro’s no is wrong it is 10^+23 [Reply](#comment-62723) 1. That’s also correct it is 6.023×10^23 [Reply](#comment-215137) 3. Very basically important question answer [Reply](#comment-248300) 4. Yes it’s right 1ml=0.001L Due to it’s A conversion factor form Milli liters to liters i.e (1/1000 of liter) [Reply](#comment-262881) 5. Nice question [Reply](#comment-270366) 6. What’s the difference in your answer and above que.19th answer??😁 [Reply](#comment-276416) 2. How can we determine the boiling points of components in the mixture are far or close to each other? [Reply](#comment-40038) 1. How can u determine the rectified spirit [Reply](#comment-41449) 1. 96% alcohol + 4% water [Reply](#comment-42844) 1. what is the modern name of element ”sb” ??? [Reply](#comment-53381) 1. stibnite/antimony 2. Antimony 2. By fractional distillation or extractive distillation [Reply](#comment-64857) 1. Fractional distillation is a process of separating a mixture of chemical compounds. [Reply](#comment-277515) 3. By using ditillation metgod first smaller boiling point will come first then tha second comes [Reply](#comment-237532) 1. If the difference in boiling points of two liquid is not much, fractional distillation is used to separate them. In this technique, fractionating column is fitted over the mouth of the round bottom flask. When vapours of a liquid mixture are passed through a fractionating column, the capours of the low boiling liquid (A) will move up while those of the high boiling liquid will condense and fall back into the flask. Therefore, liquid (A) with low boiling point will distill first. [Reply](#comment-277516) 4. The ones that are more volatile evaporate fasts [Reply](#comment-270343) 3. Nice question [Reply](#comment-42623) 4. Practicle questions chemistory [Reply](#comment-42864) 5. How to make M/10 solution [Reply](#comment-43160) 1. dont know [Reply](#comment-46700) 2. Dilute solution with 100ml distilled water [Reply](#comment-186946) 3. Its molecular mass is 106\. To prepare \\frac{M}{10} Na2CO3 solution, 10.6 g of sodium carbonate should be dissolved per litre of the solution. Normally in the laboratory we are required to prepare 250 ml of solution. [Reply](#comment-277518) 6. imp question [Reply](#comment-43268) 1. Thank you [Reply](#comment-43530) 7. Nice qutions [Reply](#comment-43660) 8. Usefull questions …thnk u for give this questions.. [Reply](#comment-44313) 1. Yes very useful [Reply](#comment-286080) 9. Pls join ts Grp. Very nice and good [Reply](#comment-45675) 10. What is range of water [Reply](#comment-47385) 1. 0-14 [Reply](#comment-178148) 11. Very useful questions. thanks [Reply](#comment-47422) 12. calculate repulsive force between two electron? when the distance between then is 4.10\* -15 (four into ten two the power -15? [Reply](#comment-48335) 13. good in improview the knowledge questions. [Reply](#comment-49144) 14. What is Balance shell???? [Reply](#comment-49196) 1. Very useful .what is valance shell [Reply](#comment-110897) 1. a place outside the nucleus where an electron can move around the nucleus [Reply](#comment-178150) 15. Useful questions. but check your answer on question 19. [Reply](#comment-49434) 1. updated! Thanks for pointing this out [Reply](#comment-55732) 16. Please provide more questions [Reply](#comment-50803) 17. Excellent performance for Interview questions once again inter questions basic level [Reply](#comment-53473) 18. Nice [Reply](#comment-53651) 19. I am Abrham and I am learning an industrial chemistry in undergraduate level so I want to learn master through fast track. So to get this opportunity there is an interview, please help to answer the interview questions [Reply](#comment-54152) 20. Nice nots [Reply](#comment-56143) 21. I am chemistry student learn about in chemistry [Reply](#comment-56837) 22. Thank you for google, it gave top 22 chemistry interview questions [Reply](#comment-56961) 23. A microlitre is 10-^6 of a litre. It should read 0.000001L [Reply](#comment-58193) 1. Thanks for writing. It is updated. [Reply](#comment-167947) 24. Nice….. Do you have more questions…?? [Reply](#comment-58315) 25. PLS more interview questions on clinical chemistry [Reply](#comment-59611) 26. Thnx…..Very important questions [Reply](#comment-61002) 27. Thnx….. [Reply](#comment-61003) 28. What is mean by pH [Reply](#comment-61004) 1. Potential of hydrogen [Reply](#comment-275280) 29. Please provide 3years experience interwe qoustions [Reply](#comment-61852) 30. I ma bsc chemistry I am completely 2108 batch but freshers student [Reply](#comment-63423) 31. More important questions and answers plz [Reply](#comment-63521) 32. Really… Very useful [Reply](#comment-70008) 33. Usefull questions….tq [Reply](#comment-72883) 34. What is water properties…? [Reply](#comment-76580) 35. Plz noted That If 1 ml = 0.001 litre Then 1microlitre= 0.001 ml hence it is 0.000001 litre [Reply](#comment-82024) 1. Thanks for writing. It is updated. [Reply](#comment-167936) 36. i appritiate it thunks [Reply](#comment-83119) 37. Is is useful to freshers also [Reply](#comment-83173) 38. very nice questions [Reply](#comment-83587) 39. Pls provide more videos…its very helpful [Reply](#comment-84665) 40. Sir i have done masters in chemistry but sir i want to clear all basic [Reply](#comment-90253) 41. In 19th question Maybe 1microliter will be 0.000001 [Reply](#comment-95690) 1. Thanks for pointing out. It is updated. [Reply](#comment-167934) 42. Give more Question for interview [Reply](#comment-102880) 43. Hi Am Musrath Jahan, will have to attend content writing chemistry exam for 11th and 12 grade need specimen copy of question and answer script. Thank you. [Reply](#comment-114773) 44. Very important information [Reply](#comment-133102) 45. Give more questions for interview [Reply](#comment-134116) 1. Interview questions and answers [Reply](#comment-280823) 46. I need some more information by giving the definitions with formula Because is to learn with interest [Reply](#comment-141750) 47. Please provide more basic questions [Reply](#comment-146065) 48. Give more questions related with Msc chemistry Syllabus. [Reply](#comment-152052) 49. Nice questions [Reply](#comment-162735) 50. Very nice …I interesed to join u r group [Reply](#comment-170747) 51. I like chemistry subeject sir many more send me question and answers [Reply](#comment-176590) 52. It is very useful thanks [Reply](#comment-188759) 53. Bsc based [Reply](#comment-193668) 1. Chemistry definition [Reply](#comment-214431) 54. I am a student and I need assistant here [Reply](#comment-194443) 55. Well done I’m very appreciated with your help [Reply](#comment-197152) 56. I really appreciate this, PLS more basic questions for interview for nursing, will appreciate.email- nmombum@ Gmail.com. [Reply](#comment-207837) 57. All questions are nice but there is a mistake in 12th question. The value of avagadro no. 6.023×10^23 not 10^-23 [Reply](#comment-208686) 1. Hi, Thanks for writing. It is reviewed. [Reply](#comment-214678) 58. Chemistry definition [Reply](#comment-214432) 1. Study of physical and chemical properties [Reply](#comment-243160) 59. Question no 8 there is small mistake in ans. Use of distillation and fractionation (1st sentence) . [Reply](#comment-261092) 1. It is corrected..!! [Reply](#comment-268864) 60. Quilaty control,pharma jobs [Reply](#comment-269450) 61. Thank u sir [Reply](#comment-271499) 62. Must important Questions that’s really necessary for an Interview all questions come from basic chemistry and must know if you are a student of chemistry subject [Reply](#comment-277035) 63. good quation [Reply](#comment-278445) 64. potentiol of hydrogen [Reply](#comment-278447) ### Leave a Reply [Cancel reply](https://career.guru99.com/top-22-chemistry-interview-questions/#respond) Your email address will not be published. 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