Top 22 Chemistry Interview Questions & Answers

1)      Explain the term Aliquot and Diluent?

  • Aliquot: It is a measured sub-volume of the original sample
  • Diluent: Material with which sample is diluted

2)      What is molality?

Molality is the number of solutes that are present in 1 kg of a solvent.

3)      What is titration?

Titration is a process to determine the molarity of a base or an acid.  In this process, a reaction is carried out between the known volumes of a solution with a known concentration, against the known volume of a solution with an unknown concentration.

4)      What is a buffer?

A buffer is an aqueous solution which has highly stable pH. It is a blend of a weak acid and its conjugate base or vice versa. On adding a small amount of base or acid to buffer, its pH hardly changes.

5)      How does buffer work?

In buffer when hydrogen ion is added, it will be neutralized by the base in the buffer.  Hydroxide ion will be neutralized by the acid.  On the overall pH of the buffer solution, these neutralization reactions will not show much effect.

While when you select an acid as a buffer solution, try to use an acid that has a pH closed to your desired pH.  This will help your buffer to achieve a nearly equivalent amount of acid and conjugate base, so that it will enable to neutralize as much as H+ and OH -.


6)      What is a mole?

Mole is the unit used to define the number of chemical substance present in a substance. It is the amount of substance which consists of the same number of chemical units as there are atoms in exactly 12 gram of pure carbon-12.

7)      How will you calculate how many moles of glucose present in 320 mL of 5.0 M of glucose solution?

First step: Convert the volume from millilitres to litres

  • 320  X (1 litre/1000mL) = 0.320 L solution

Second use the formula = M x V

= 5.0 moles glucose/ litre solution X 0.320 L solution

= 1.6 moles of glucose present in 320mL of solution

8)      Explain what is the difference between fractionation and distillation?

Both methods are used to separate the components present in the solution based on the melting points

  • Distillation: This technique is used when the boiling point of chemicals are different in the mixtures
  • Fractionation: This technique is used when the boiling point of chemicals are close to each other in the mixtures

9)      Mention the formula to calculate pH of a solution?

In order to calculate the pH of a solution you have to use the formula pH= -log [H+] or pH = -log [H3O+]

10)   What is the difference between Molarity and Normality?

Both techniques are used to the amount of chemical present in the solution.  However, they are almost similar but differs in

                           Molarity                            Normality
–          Molarity is used to know the total amount of molecules in a 1-liter solution –          Normality is used to know the total number of reactive units in 1 liter of solution
–          It is expressed as moles of a compound per litre of solution –          It is expressed in equivalent per litre

11)   What is Valency?

Valency is a property of groups or atoms, equal to the number of atoms of hydrogen that the group or atom could combine with or displace it in forming compounds.

12)   Define Avogadro’s law?

According to Avogadro’s law, at the same temperature and pressure, an equal volume of gases contains the same number of molecules regardless of the chemical nature and physical properties.

Avogadro’s number = 6.023 X 10 (-23)

13)    Explain what makes a molecule into organic molecule?

In a molecule when a hydrogen atom is less than the ratio of the carbon atom, then such molecules are referred to as an organic molecule.

14)   Which metal is used to extract copper from the solution of copper sulfate?

Fe or ferrous is the metal that is used to extract copper from the solution of copper sulphate.

15)   Explain what is the chemical composition of fat in the human body?

The fat found in the human body is mainly composed of

  • Glycerides
  • Glycerides+Phospholipids
  • Glycolipids
  • Phosphoinositides
  • Tocopherol

16)   What is the monomer of polyethylene?

The monomer of polyethylene is ethylene

17)   What is the formula you will use to calculate how many milliliters of 5.5 M NaOH are required to prepare 400 mL of 1.5M NaOH?

To know the amount or volume of NaOH to prepare 400 mL of 1.5 M NaOH, we use formula

M1 X V1 = M2 X V2

V1 = M2 X V2/ M1

But before that we will convert 400 mL into litre = 0.4 L

5.5 X V1 = 1.5 M x 0.4 L

V1 = 1.5 M X 0.4L/ 5.5

V1= 0.10 L

V1 = 100mL

So, you need 100mL of 5.5 NaOH

18)   Why graphite rod is used in nuclear reactor?

A graphite rod is used in a nuclear reactor allows un-enriched uranium to be used as a nuclear fuel.

19)   Mention how many milliliters is equal to 1 liter and how many microliters is equal to liter?

  • 1 millilitre = 0.001 litre
  • 1 microliter = 0.000001 litre

20)   What is oxidation and reduction reaction?

  • Oxidation = When there is a loss of hydrogen or electrons OR gain of oxygen is known as Oxidation reaction.
  • Reduction = When there is a gain of hydrogen or electron OR loss of oxygen is known as a reduction reaction

Example of oxidation-reduction reaction is observed in the human body when an electron is transferred into the cell and oxidation of glucose take place from which we get the energy.

21)   What does iron ore consist of?

Iron ore is consists of Fe2O3

22)   Explain what is dextro-rotatory and levorotatory?

Levorotation and Dextrorotation are referred to the properties of plane polarized light when light rotates clockwise when it approaches the observer is then known as dextro-rotation, and when the light rotates anti-clockwise then it is referred as levorotation.

A compound which exhibits a dextro-rotation is referred to as dextro-rotatory and which exhibits levorotation is referred to as levorotatory.

65 replies

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  1. Avatar
    Doris says:

    Number 19 isn’t correct. 1ml = 0.001L and so on

    • Avatar
      Firdous Hanif sayyed says:

      1milliliter =0.0001

      • Avatar
        AL W says:

        1 millilitre is one 1000th of a litre – therefore 1ml = 0.001L

        • Avatar
          admin says:

          updated! Thanks for pointing this out

          • Avatar
            Vineet Kumar says:

            How to prepare solution in ppm

    • Avatar
      Madhuri Ingale says:

      Avogadro’s no is wrong it is 10^+23

  2. Avatar
    Kishor K says:

    How can we determine the boiling points of components in the mixture are far or close to each other?

    • Avatar
      Devi says:

      How can u determine the rectified spirit

      • Avatar
        Yash says:

        96% alcohol + 4% water

        • Avatar
          basit says:

          what is the modern name of element ”sb” ???

    • Avatar
      Sagar patel says:

      By fractional distillation or extractive distillation

  3. Avatar
    Amol patil says:

    Nice question

  4. Avatar
    kundan kumar says:

    Practicle questions chemistory

  5. Avatar
    ARJUN says:

    How to make M/10 solution

    • Avatar
      pwoliyan AKSHAI says:

      dont know

  6. Avatar
    rahul jadhav says:

    imp question

    • Avatar
      Gayake vaibhav says:

      Thank you

  7. Avatar
    Santhosh chitti says:

    Nice qutions

  8. Avatar
    Ravina says:

    Usefull questions …thnk u for give this questions..

  9. Avatar
    Sakthynivedha says:

    Pls join ts Grp. Very nice and good

  10. Avatar
    Kumar says:

    What is range of water

  11. Avatar
    Chetan Bagora says:

    Very useful questions. thanks

  12. Avatar
    Gopabandhu Majhi says:

    calculate repulsive force between two electron? when the distance between then is 4.10* -15 (four into ten two the power -15?

  13. Avatar
    Murugesan.p says:

    good in improview the knowledge questions.

  14. Avatar
    Umesh says:

    What is Balance shell????

    • Avatar
      D. Joys says:

      Very useful .what is valance shell

  15. Avatar
    cathy says:

    Useful questions. but check your answer on question 19.

    • Avatar
      admin says:

      updated! Thanks for pointing this out

  16. Avatar
    Sandeepreddy says:

    Please provide more questions

  17. Avatar
    Azim Ghanchi says:

    Excellent performance for Interview questions once again inter questions basic level

  18. Avatar
    Balaabishek says:


  19. Avatar
    Abrham mengstu says:

    I am Abrham and I am learning an industrial chemistry in undergraduate level so I want to learn master through fast track. So to get this opportunity there is an interview, please help to answer the interview questions

  20. Avatar
    Jalindar sutar says:

    Nice nots

  21. Avatar
    Sandeep Kamble says:

    I am chemistry student learn about in chemistry

  22. Avatar
    M. Naveenkumar says:

    Thank you for google, it gave top 22 chemistry interview questions

  23. Avatar
    Alessa says:

    A microlitre is 10-^6 of a litre. It should read 0.000001L

    • Avatar
      Krishna says:

      Thanks for writing. It is updated.

  24. Avatar
    Mayur says:

    Nice….. Do you have more questions…??

  25. Avatar
    Enowo says:

    PLS more interview questions on clinical chemistry

  26. Avatar
    Prashant lad says:

    Thnx…..Very important questions

  27. Avatar
    Prashant lad says:


  28. Avatar
    Prashant lad says:

    What is mean by pH

  29. Avatar
    Routhu Jagadeesh says:

    Please provide 3years experience interwe qoustions

  30. Avatar
    Parthiban says:

    I ma bsc chemistry I am completely 2108 batch but freshers student

  31. Avatar
    Ankita Vishal Kadam says:

    More important questions and answers plz

  32. Avatar
    Harsha says:

    Really… Very useful

  33. Avatar
    Ambarish Nalatawad says:

    Usefull questions….tq

  34. Avatar
    Harkesh Raut says:

    What is water properties…?

  35. Avatar
    Swaraj jadhav says:

    Plz noted That
    If 1 ml = 0.001 litre
    Then 1microlitre= 0.001 ml hence it is 0.000001 litre

    • Avatar
      Krishna says:

      Thanks for writing. It is updated.

  36. Avatar
    yobsan abdena says:

    i appritiate it thunks

  37. Avatar
    Narender says:

    Is is useful to freshers also

  38. Avatar
    vandana says:

    very nice questions

  39. Avatar
    Dinesh tulshiram Mistari says:

    Pls provide more videos…its very helpful

  40. Avatar
    Mehak says:

    Sir i have done masters in chemistry but sir i want to clear all basic

  41. Avatar
    S D says:

    In 19th question Maybe 1microliter will be 0.000001

    • Avatar
      Krishna says:

      Thanks for pointing out. It is updated.

  42. Avatar
    Marmat bhagyashri motilal says:

    Give more Question for interview

  43. Avatar
    Musrath Jahan says:

    Am Musrath Jahan, will have to attend content writing chemistry exam for 11th and 12 grade need specimen copy of question and answer script.

    Thank you.

  44. Avatar
    Azhar mahmood says:

    Very important information

  45. Avatar
    Veeresh says:

    Give more questions for interview

  46. Avatar
    Kampe sandeep says:

    I need some more information by giving the definitions with formula
    Because is to learn with interest

  47. Avatar
    Niranjan Talange says:

    Please provide more basic questions

  48. Avatar
    Pagire Ramdas V. says:

    Give more questions related with Msc chemistry Syllabus.

  49. Avatar
    Sandhya G says:

    Nice questions